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Dosage

Tirzepatide dosage chart

Label dose steps for every tirzepatide brand on one page.

Clinician review pending Updated

Zepbound dosage

DoseFastest label timingNote
2.5 mgWeeks 1 to 4Starting dose. It is not a maintenance dose: it gives your gut time to adjust.
5 mgWeeks 5 to 8First maintenance option on the label.
7.5 mgWeeks 9 to 12Step between maintenance doses.
10 mgWeeks 13 to 16Maintenance option; also a label dose for sleep apnea.
12.5 mgWeeks 17 to 20Step between maintenance doses.
15 mgWeek 21 onwardHighest dose on the label.

5 mg, 10 mg or 15 mg once weekly (10 mg or 15 mg for sleep apnea)

Mounjaro dosage

DoseFastest label timingNote
2.5 mgWeeks 1 to 4Starting dose. Not meant to control blood sugar on its own.
5 mgWeeks 5 to 8First maintenance option.
7.5 mgWeeks 9 to 12Maintenance option if more blood sugar control is needed.
10 mgWeeks 13 to 16Maintenance option.
12.5 mgWeeks 17 to 20Maintenance option.
15 mgWeek 21 onwardHighest dose on the label.

5 mg to 15 mg once weekly

Explainer · 0:22

START LOW 2.5 mg weeks 1 to 4 Not a maintenance dose it's there to let your stomach adjust STEP UP SLOWLY 2.557.51012.515 mg each step: 4+ weeks SIDE EFFECTS FOLLOW THE STEPS +2.5 mg+2.5 mg+2.5 mg+2.5 mg flare, then settle how often nausea is reported IT'S OK TO HOLD 7.5 mg · held on-label, common 0:22 · voiced · captions on
GLP-1 doses start low. Zepbound starts at 2.5 mg, a starter dose that gives your gut time to adjust.
0:00 / 0:22
Why GLP-1 doses go up slowly
Read the transcript
  1. GLP-1 doses start low. Zepbound starts at 2.5 mg, a starter dose that gives your gut time to adjust.
  2. After at least 4 weeks, your prescriber may step it up by 2.5 mg, up to a maintenance dose of 5, 10 or 15 mg.
  3. Stomach side effects like nausea often flare for a few days after each increase, then settle on the same dose.
  4. Staying on a dose longer is common and allowed by the label. Never increase faster than your prescription says.

Clinician review pending. Drafted from primary sources and waiting for sign-off by a licensed clinician (MD, DO or PharmD) before launch. Every number is checked against its source. Drug facts are re-checked quarterly, prices monthly and whenever a label changes. How we review · Report an error