Side effects A to Z
Nausea
Nausea is the single most reported side effect in the big GLP-1 weight trials, and it tend…
OpenVomiting
Vomiting on a GLP-1 is less common than nausea, but it is the stomach side effect most lik…
OpenDiarrhea
Diarrhea is one of the top stomach side effects in GLP-1 trials, and high-fat meals are a …
OpenConstipation
Eating less food means less bulk moving through your gut, so constipation on a GLP-1 can b…
OpenStomach pain
Most belly discomfort on a GLP-1 is mild cramping or fullness, but one pattern, severe pai…
OpenHeartburn and indigestion
Heartburn on a GLP-1 often has less to do with spicy food and more to do with a full stoma…
OpenBurping
Sulfur burps, the rotten-egg kind, are a side effect people talk about online far more tha…
OpenBloating
Bloating on a GLP-1 can make you feel full for hours after a small meal, which is the drug…
OpenGas
More gas on a GLP-1 is common, and the high-fiber, high-protein foods people add to stay h…
OpenHeadache
Headaches on a GLP-1 often trace back to something simple: eating and drinking much less t…
OpenFatigue
If you are eating hundreds of calories less than before, feeling tired is often your energ…
OpenDizziness
Feeling lightheaded when you stand up on a GLP-1 can be a quiet sign you are not drinking …
OpenHair loss
Hair shedding on a GLP-1 usually shows up months after weight loss starts, which is why ma…
OpenInjection-site reactions
Redness or itching where you inject is usually mild and short-lived, and rotating sites ea…
OpenLow blood sugar
GLP-1 medicines rarely cause low blood sugar on their own, but the risk jumps when they ar…
OpenDecreased appetite
Losing your appetite is the point of a GLP-1, until it drops so low that you stop getting …
OpenStomach side effects by medicine
| Medicine | Nausea | Vomiting | Diarrhea | Constipation | Stomach pain |
|---|---|---|---|---|---|
| Zepbound | 25% to 29% | 8% to 13% | 19% to 23% | 11% to 17% | 9% to 10% |
| Wegovy | 44% | 24% | 30% | 24% | 20% |
| Ozempic | 16% to 20% | 5% to 9% | 9% | 3% to 5% | 6% to 7% |
| Mounjaro | 12% to 18% | 5% to 9% | 12% to 17% | 6% to 7% | 5% to 6% |
| Rybelsus | 11% to 20% | 6% to 8% | 9% to 10% | 5% to 6% | 10% to 11% |
| Saxenda | 39% | 16% | 21% | 19% | 5% |
| Trulicity | 12% to 21% | 6% to 13% | 9% to 13% | not in table | 7% to 9% |
| Victoza | 18% to 20% | 6% to 9% | 10% to 12% | 5% | not in table |
Label rates on the drug (ranges span doses). "Not in table" means the label's common-reaction table doesn't list it.
How to use it
- Enter your numbers. Switch between US and metric units at any time.
- Results update as you type, and the formula is shown so you can check it.
- Copy the link, save the plan on this device, or print it for your next appointment.
These are estimates, not a diagnosis. A clinician can account for your health history and medicines.
Clinician review pending. Drafted from primary sources and waiting for sign-off by a licensed clinician (MD, DO or PharmD) before launch. Every number is checked against its source. Drug facts are re-checked quarterly, prices monthly and whenever a label changes. How we review · Report an error