Skip to content

Dose step 2 of 6

Mounjaro 5 mg

You've just stepped up from 2.5 mg. Nausea and other stomach effects often flare for a few days after an increase, then settle on the same dose.

Clinician review pending Updated
Step
2 of 6
on the label
Timing
wk 5 to 8
fastest schedule
Length
4 weeks
minimum
Next step
7.5 mg
if prescribed

Where 5 mg sits on the ladder

What the label says

Mounjaro 5 mg: First maintenance option.

You've just stepped up from 2.5 mg. Nausea and other stomach effects often flare for a few days after an increase, then settle on the same dose.

Most common side effects on Mounjaro

Side effectMounjaroPlacebo
Nausea12% to 18%4%
Diarrhea12% to 17%9%
Decreased appetite5% to 11%1%

Rates across all label doses, not this step alone. Pooled placebo-controlled type 2 diabetes trials in the Mounjaro label (5 mg, 10 mg and 15 mg).

Is 5 mg a maintenance dose?

Yes. The label lists maintenance as 5 mg to 15 mg once weekly.

Common questions

How long do you stay on Mounjaro 5 mg?

At least 4 weeks on the label before any increase. Many people stay longer.

What comes after Mounjaro 5 mg?

The next label step is 7.5 mg, if your prescriber increases it.

Can you stay on Mounjaro 5 mg longer?

Yes. Holding a dose longer is common when side effects need time to settle. Your prescriber decides.

Sources

  1. Mounjaro prescribing information (FDA label on DailyMed)
  2. SURPASS-2 trial publication

Clinician review pending. Drafted from primary sources and waiting for sign-off by a licensed clinician (MD, DO or PharmD) before launch. Every number is checked against its source. Drug facts are re-checked quarterly, prices monthly and whenever a label changes. How we review · Report an error