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Supplements

NAD+ injections

NAD+ injections and IV drips are sold by clinics for energy, aging and weight loss, but no NAD+ injection is FDA-approved and human evidence is limited.

Clinician review pending Updated Supplements
DefinitionNAD+ injections and IV drips are sold by clinics for energy, aging and weight loss, but no NAD+ injection is FDA-approved and human evidence is limited.

What it means

NAD+ (nicotinamide adenine dinucleotide) is a molecule every cell uses to turn food into energy. Levels tend to fall with age, which has made it popular in anti-aging marketing.

Wellness clinics and some telehealth companies offer NAD+ as an IV drip or a shot, often compounded. No NAD+ injection product is FDA-approved for weight loss or any other use.

Human research mostly involves pills of NAD+ building blocks, such as nicotinamide riboside. Those trials are small and short and have not shown meaningful weight loss. Evidence for injected NAD+ is thinner still.

People report side effects during infusions such as flushing, nausea and chest tightness, especially when given quickly. Because products are compounded, quality depends on the pharmacy. Ask what you are paying for and what evidence supports it.

Why it matters

NAD+ shots are often bundled with GLP-1 programs, adding cost without proven weight benefit.

Related terms

B12 injectionsLipotropic injections (MIC shots)Compounded drugDo supplements help with weight loss

Sources

  1. PubMed: NAD+ precursor supplementation trials in humans

Clinician review pending. Drafted from primary sources and waiting for sign-off by a licensed clinician (MD, DO or PharmD) before launch. Every number is checked against its source. Drug facts are re-checked quarterly, prices monthly and whenever a label changes. How we review · Report an error