Placebo-controlled weight-management trials in the Wegovy label (2.4 mg).
Constipation across GLP-1 medicines
Why it happens
GLP-1 medicines slow the movement of food through the digestive tract. Slower transit gives the colon more time to pull water out of stool, which makes it harder and less frequent.
At the same time, many people eat and drink much less than before. Less food and fluid means less volume to keep things moving.
When it starts and fades
Constipation can begin early and may linger beyond the step-up phase for some people. In trials it was reported most often during dose escalation and was usually mild to moderate.
If you go several days without a bowel movement, or have hard, painful stools despite home measures, check in with your care team.
What helps
- Drink water steadily through the day, aiming above your old baseline since food water drops.
- Add fiber from vegetables, beans, berries, oats or chia, increasing slowly.
- Take a daily walk; movement helps the gut move too.
- Keep a regular bathroom time and do not ignore the urge to go.
- Ask a pharmacist which over-the-counter options are a fit before trying one.
- Include some healthy fat, which can help stool pass.
How to use it
- Enter your numbers. Switch between US and metric units at any time.
- Results update as you type, and the formula is shown so you can check it.
- Copy the link, save the plan on this device, or print it for your next appointment.

These are estimates, not a diagnosis. A clinician can account for your health history and medicines.
Other Wegovy side effects
Common questions
How common is constipation on Wegovy?
In the trials behind the label, 24% of people on Wegovy reported it, vs 11% on placebo.
How do I relieve constipation on Wegovy?
Start with more water, fiber added slowly and daily movement. Ask your pharmacist or prescriber before using laxatives regularly.
Does GLP-1 constipation go away?
For many people it improves after the step-up phase, but some deal with it longer. Consistent habits usually help more than one-time fixes.
Can protein shakes make constipation worse?
Some can, especially if they replace fiber-rich food. Pair shakes with fruit, vegetables or a fiber source and extra fluids.
Sources
Clinician review pending. Drafted from primary sources and waiting for sign-off by a licensed clinician (MD, DO or PharmD) before launch. Every number is checked against its source. Drug facts are re-checked quarterly, prices monthly and whenever a label changes. How we review · Report an error