Where 4.5 mg sits on the ladder
What the label says
Trulicity 4.5 mg: If more control is needed after at least 4 weeks on 3 mg. Highest dose.
This is the highest dose on the label. Once here, most people stay on it unless side effects or their prescriber's plan say otherwise.
Most common side effects on Trulicity
Rates across all label doses, not this step alone. Placebo-controlled trials in the Trulicity label (0.75 mg and 1.5 mg).
Is 4.5 mg a maintenance dose?
Yes. The label lists maintenance as 0.75 mg to 4.5 mg once weekly.
How to use it
- Enter your numbers. Switch between US and metric units at any time.
- Results update as you type, and the formula is shown so you can check it.
- Copy the link, save the plan on this device, or print it for your next appointment.

These are estimates, not a diagnosis. A clinician can account for your health history and medicines.
Common questions
How long do you stay on Trulicity 4.5 mg?
There's no set end; it's the highest label dose.
What comes after Trulicity 4.5 mg?
Nothing. It's the highest dose on the label.
Can you stay on Trulicity 4.5 mg longer?
Yes. Holding a dose longer is common when side effects need time to settle. Your prescriber decides.
Sources
Clinician review pending. Drafted from primary sources and waiting for sign-off by a licensed clinician (MD, DO or PharmD) before launch. Every number is checked against its source. Drug facts are re-checked quarterly, prices monthly and whenever a label changes. How we review · Report an error