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Dose step 4 of 4

Trulicity 4.5 mg

This is the highest dose on the label. Once here, most people stay on it unless side effects or their prescriber's plan say otherwise.

Clinician review pending Updated
Step
4 of 4
on the label
Timing
wk 13 onward
fastest schedule
Length
ongoing
Next step
none
highest dose

Where 4.5 mg sits on the ladder

What the label says

Trulicity 4.5 mg: If more control is needed after at least 4 weeks on 3 mg. Highest dose.

This is the highest dose on the label. Once here, most people stay on it unless side effects or their prescriber's plan say otherwise.

Most common side effects on Trulicity

Side effectTrulicityPlacebo
Nausea12% to 21%5%
Diarrhea9% to 13%7%
Vomiting6% to 13%2%

Rates across all label doses, not this step alone. Placebo-controlled trials in the Trulicity label (0.75 mg and 1.5 mg).

Is 4.5 mg a maintenance dose?

Yes. The label lists maintenance as 0.75 mg to 4.5 mg once weekly.

Common questions

How long do you stay on Trulicity 4.5 mg?

There's no set end; it's the highest label dose.

What comes after Trulicity 4.5 mg?

Nothing. It's the highest dose on the label.

Can you stay on Trulicity 4.5 mg longer?

Yes. Holding a dose longer is common when side effects need time to settle. Your prescriber decides.

Sources

  1. Trulicity prescribing information (FDA label on DailyMed)

Clinician review pending. Drafted from primary sources and waiting for sign-off by a licensed clinician (MD, DO or PharmD) before launch. Every number is checked against its source. Drug facts are re-checked quarterly, prices monthly and whenever a label changes. How we review · Report an error