Skip to content

Projection · SCALE Obesity and Prediabetes

Saxenda weight loss from 400 lb

If you match the trial average at 3 mg, you'd be about 368 lb by week 56.

Clinician review pending Updated
Avg loss by week 56
−32lb
3 mg, 8.0%
Weight at week 56
368lb
if you match the average
Placebo group
−10lb
2.6%, same trial
Trial length
56weeks
SCALE Obesity and Prediabetes
Show the math
Loss = 400 lb × 8.0% = 32 lb
Projected weight from 400 lb
365375384393403091928374756weeks

Saxenda 3 mgPlacebo

Week by week

WeekSaxenda 3 mg
Week 4−6 lb · 394
Week 8−12 lb · 388
Week 12−16 lb · 384
Week 16−19 lb · 381
Week 24−24 lb · 376
Week 36−29 lb · 371
Week 52−32 lb · 368
Week 56−32 lb · 368

Pounds lost · weight. A curve shaped to the trial endpoint, not trial data for each week.

What each milestone means at 400 lb

LossPoundsNew weight
5%20 lb380 lb
10%40 lb360 lb
15%60 lb340 lb
20%80 lb320 lb
25%100 lb300 lb

About 63% lost at least 5% and about 33% lost at least 10%.

How this projection works

We take the average loss reported in SCALE Obesity and Prediabetes (3,731 adults with obesity or overweight, without diabetes) and fit a smooth curve that reaches it at week 56. Real progress is lumpier: early weeks include water, increases follow the dose steps, and individual results range widely around the average. Diet and activity changes were part of the trial for everyone, including placebo.

Other start weights

Common questions

How much weight can you lose on Saxenda at 400 lb?

If you matched the SCALE Obesity and Prediabetes average at 3 mg (8.0%), you'd lose about 32 lb over 56 weeks. Many people lose more or less.

How fast does Saxenda weight loss happen?

Loss is fastest in the first months and slows as you near the plateau. By week 24, the curve here shows about 24 lb at 3 mg.

Is this a guarantee?

No. It's an average from a trial, applied to your start weight. Your prescriber and your own weigh-ins are the real guide.

Sources

  1. Saxenda prescribing information (FDA label on DailyMed)
  2. SCALE Obesity and Prediabetes trial publication

Clinician review pending. Drafted from primary sources and waiting for sign-off by a licensed clinician (MD, DO or PharmD) before launch. Every number is checked against its source. Drug facts are re-checked quarterly, prices monthly and whenever a label changes. How we review · Report an error