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Medicines and devices

Subcutaneous injection

A subcutaneous injection delivers medicine into the fatty layer just under the skin, the route used for injected GLP-1 medicines and insulin.

DefinitionA subcutaneous injection delivers medicine into the fatty layer just under the skin, the route used for injected GLP-1 medicines and insulin.

What it means

"Subcutaneous" means under the skin. The medicine goes into the layer of fat between the skin and muscle, where it is absorbed slowly and steadily into the blood. Needles for this route are short and thin.

All the injected GLP-1 medicines on this site are given this way, usually in the stomach area, the front of the thigh or the back of the upper arm. Each label lists the allowed sites.

Other routes include intramuscular injections, which go deeper into muscle, as with some vitamin B12 shots, and intravenous injections into a vein. A medicine labeled for one route should not be given by another.

Mild redness, itching or a small bump where you injected can happen. Rotating sites, letting the pen or vial reach room temperature if the label allows, and injecting into healthy skin can help.

Why it matters

Understanding the route helps you inject correctly and explains why sites need rotating.

Related terms

Sources

  1. DailyMed: Wegovy label and instructions for use

Clinician review pending. Drafted from primary sources and waiting for sign-off by a licensed clinician (MD, DO or PharmD) before launch. Every number is checked against its source. Drug facts are re-checked quarterly, prices monthly and whenever a label changes. How we review · Report an error