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Dosage

Semaglutide dosage chart

Label dose steps for every semaglutide brand on one page.

Clinician review pending Updated

Wegovy dosage

DoseFastest label timingNote
0.25 mgWeeks 1 to 4Starting dose for weeks 1 to 4. Not a maintenance dose.
0.5 mgWeeks 5 to 8Weeks 5 to 8.
1 mgWeeks 9 to 12Weeks 9 to 12.
1.7 mgWeeks 13 to 16Weeks 13 to 16. Can be a maintenance dose if 2.4 mg isn't tolerated.
2.4 mgWeek 17 onwardUsual maintenance dose from week 17.

2.4 mg once weekly (1.7 mg if 2.4 mg isn't tolerated)

Ozempic dosage

DoseFastest label timingNote
0.25 mgWeeks 1 to 4Starting dose. Not meant to control blood sugar on its own.
0.5 mgWeeks 5 to 8First maintenance dose.
1 mgWeeks 9 to 12If more blood sugar control is needed after at least 4 weeks on 0.5 mg.
2 mgWeek 13 onwardIf more control is needed after at least 4 weeks on 1 mg. Highest dose on the label.

0.5 mg, 1 mg or 2 mg once weekly

Wegovy pill dosage

DoseFastest label timingNote
1.5 mg30 daysStarting dose for the first 30 days.
4 mg30 daysDays 31 to 60.
9 mg30 daysDays 61 to 90.
25 mgongoingMaintenance dose from day 91.

25 mg once daily

Rybelsus dosage

DoseFastest label timingNote
3 mg30 daysStarting dose for 30 days. Not meant to control blood sugar on its own.
7 mg30 daysMaintenance dose.
14 mgongoingIf more control is needed after at least 30 days on 7 mg.

7 mg or 14 mg once daily (a newer tablet formulation uses 1.5 mg, 4 mg and 9 mg strengths; check your label)

Explainer · 0:22

START LOW 2.5 mg weeks 1 to 4 Not a maintenance dose it's there to let your stomach adjust STEP UP SLOWLY 2.557.51012.515 mg each step: 4+ weeks SIDE EFFECTS FOLLOW THE STEPS +2.5 mg+2.5 mg+2.5 mg+2.5 mg flare, then settle how often nausea is reported IT'S OK TO HOLD 7.5 mg · held on-label, common 0:22 · voiced · captions on
GLP-1 doses start low. Zepbound starts at 2.5 mg, a starter dose that gives your gut time to adjust.
0:00 / 0:22
Why GLP-1 doses go up slowly
Read the transcript
  1. GLP-1 doses start low. Zepbound starts at 2.5 mg, a starter dose that gives your gut time to adjust.
  2. After at least 4 weeks, your prescriber may step it up by 2.5 mg, up to a maintenance dose of 5, 10 or 15 mg.
  3. Stomach side effects like nausea often flare for a few days after each increase, then settle on the same dose.
  4. Staying on a dose longer is common and allowed by the label. Never increase faster than your prescription says.

Clinician review pending. Drafted from primary sources and waiting for sign-off by a licensed clinician (MD, DO or PharmD) before launch. Every number is checked against its source. Drug facts are re-checked quarterly, prices monthly and whenever a label changes. How we review · Report an error