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Conditions

Chronic kidney disease (CKD)

Chronic kidney disease is long-lasting kidney damage or reduced kidney function, which means the kidneys cannot filter waste and extra fluid from the blood as well as they should.

Clinician review pending Updated Conditions
DefinitionChronic kidney disease is long-lasting kidney damage or reduced kidney function, which means the kidneys cannot filter waste and extra fluid from the blood as well as they should.

What it means

Diabetes and high blood pressure are the most common causes of CKD in adults. Heart disease and a family history of kidney disease also raise the risk. Early CKD usually causes no symptoms, so testing is often the only way to find it.

Two tests are used together: a blood test that estimates filtering function, called eGFR, and a urine test that checks for albumin, a protein that leaks into urine when the kidneys are damaged.

Ozempic has an approved use to reduce the risk of worsening kidney disease, kidney failure and death from heart disease in adults with type 2 diabetes and CKD.

GLP-1 labels also warn that vomiting, diarrhea and dehydration can lead to sudden kidney injury, and that this has occurred in people with and without kidney disease. People with CKD should ask before raising protein intake, since needs can differ.

Why it matters

Kidney function affects protein targets, fluid advice and how closely a prescriber monitors you on a GLP-1.

Related tools

Related terms

Sources

  1. NIDDK: Chronic kidney disease (CKD)
  2. MedlinePlus: eGFR and GFR tests

Clinician review pending. Drafted from primary sources and waiting for sign-off by a licensed clinician (MD, DO or PharmD) before launch. Every number is checked against its source. Drug facts are re-checked quarterly, prices monthly and whenever a label changes. How we review · Report an error