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Comparison

Wegovy vs Victoza

The facts that differ, side by side, from each FDA label and trial.

Clinician review pending Updated

Wegovy

semaglutide · Novo Nordisk

vs

Victoza

liraglutide · Novo Nordisk

Side by side

WegovyVictoza
Active ingredientsemaglutideliraglutide
MakerNovo NordiskNovo Nordisk
ClassGLP-1 receptor agonistGLP-1 receptor agonist
Approved forWeight managementType 2 diabetes
How you take itonce weekly injectiononce daily injection
Starting dose0.25 mg0.6 mg
Highest dose2.4 mg1.8 mg
Main trial result14.9% avg loss (STEP 1, 2.4 mg, 68 wk)A1C fell about 1 to 1.5 points, with modest weight loss of a few pounds
Nausea (label)44% vs 16% placebo18% to 20% vs 5% placebo
Missed-dose windowuntil 2 days (48 hours) before the next doseresume the next day (more than 3 days missed: restart at 0.6 mg)
Out of the fridgeUp to 28 days at 46°F to 86°F (8°C to 30°C)Up to 30 days after first use at 59°F to 86°F
List price$1,349/mo$816/mo
Lowest self-pay$199/monot offered

Prices compiled mid-2026 from manufacturer announcements; re-checked monthly.

Key differences

  • Different molecules. Wegovy is semaglutide (GLP-1 receptor agonist); Victoza is liraglutide (GLP-1 receptor agonist).
  • Different approvals. Wegovy is approved for weight management; Victoza is approved for type 2 diabetes. That shapes insurance coverage.
  • Different routine. Wegovy is a once weekly injection; Victoza is a once daily injection.

Trial weight loss

Wegovy 2.4 mgSTEP 1 · 68 wk
14.9%
Average % of body weight lost in each drug's main trial. Separate trials, not a head-to-head result.

Which one fits you

That's a decision for you and your prescriber. The factors that usually decide it:

  • Your diagnosis, which decides the approved option and often the coverage
  • Whether your plan covers one and not the other
  • A shot or a pill, weekly or daily
  • How you tolerate side effects
  • Cost if you pay yourself: see the cost index

Common questions

Is Wegovy the same as Victoza?

No. They contain different medicines: semaglutide and liraglutide.

Which works better for weight loss, Wegovy or Victoza?

Their main trials were separate, so a direct ranking isn't possible from that data. Your prescriber can weigh your history.

Can I switch from Wegovy to Victoza?

Only with your prescriber. Switching usually means a new starting dose, not a direct swap.

Which is cheaper, Wegovy or Victoza?

List prices are $1,349/mo and $816/mo a month; lowest self-pay options we track are $199/mo and not offered. Coverage usually matters more.

Sources

  1. Wegovy prescribing information (FDA label on DailyMed)
  2. STEP 1 trial publication
  3. Victoza prescribing information (FDA label on DailyMed)

Clinician review pending. Drafted from primary sources and waiting for sign-off by a licensed clinician (MD, DO or PharmD) before launch. Every number is checked against its source. Drug facts are re-checked quarterly, prices monthly and whenever a label changes. How we review · Report an error