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Glossary

What is Setmelanotide (Imcivree)?

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Setmelanotide (Imcivree)

Setmelanotide is a daily injection that activates the MC4R appetite pathway, approved only for certain rare genetic and hypothalamic causes of obesity.

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In plain words

Setmelanotide switches on the MC4R receptor in the brain, part of a pathway that tells the body it has enough energy stored.

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Why it matters

Setmelanotide shows that some obesity has a single, treatable cause, but it is not a general weight-loss drug.

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Setmelanotide is a daily injection that activates the MC4R appetite pathway, approved only for certain rare genetic and hypothalamic causes of obesity.

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