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Glossary

What is PYY (peptide YY)?

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PYY (peptide YY)

PYY is a gut hormone released after meals, from the same intestinal cells that make GLP-1, that helps reduce appetite and food intake.

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In plain words

Peptide YY is made by L-cells in the lower small intestine and colon, the same cells that release GLP-1.

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Why it matters

PYY helps explain why protein-rich meals and some surgeries affect fullness, and it remains a target for future drugs.

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PYY is a gut hormone released after meals, from the same intestinal cells that make GLP-1, that helps reduce appetite and food intake.

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