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Side effect

Stomach pain on GLP-1 medicines: what helps

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Photo: Tara Clark / Unsplash

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Stomach pain on GLP-1s

Most belly discomfort on a GLP-1 is mild cramping or fullness, but one pattern, severe pain that spreads to the back, is a reason to stop and get checked right away.

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Why it happens

Slower stomach emptying and changes in gut movement can cause cramping, fullness and gas pain.

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When it shows up

Mild belly pain is most common in the early weeks and after dose steps, in line with other stomach side effects in trials, which were…

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What helps

Eat smaller meals and slow down at the table.

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What helps

Limit fatty and fried foods, which can worsen fullness and cramping.

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Call your doctor if

Severe stomach pain that will not go away, with or without vomiting, especially if it spreads to your back, which can be a sign of pancreatitis.

Want the full picture?

Mild cramping, fullness and gassy pain are common, especially around dose increases. Severe or persistent pain is different and can signal pancreatitis or

Tap below for the full page. Not medical advice; talk to your clinician about your care.

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