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Medications

Which GLP-1 is best for weight loss

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Which GLP-1 is best?

The honest answer has two parts: the trial numbers, and what fits your life.
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Biggest average loss

Zepbound 15 mg averaged 20.9% weight loss over 72 weeks in SURMOUNT-1.
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The longest track record

Wegovy averaged 14.9% in STEP 1 and is also approved to lower heart risk.
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Head to head

In SURMOUNT-5, tirzepatide averaged about 20.2% vs about 13.7% for semaglutide.
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Best is personal

Coverage, side effects and shot vs pill all matter as much as the number.
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Your next step

Project your own loss, then talk it through with a licensed clinician.

Want the full picture?

Zepbound, Wegovy, the Wegovy pill and Saxenda compared by trial results, side effects and routine, and why the best GLP-1 depends on you.

Tap below for the full page. Not medical advice; talk to your clinician about your care.

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